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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XDH
All Species:
11.82
Human Site:
S475
Identified Species:
26
UniProt:
P47989
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P47989
NP_000370.2
1333
146424
S475
K
T
T
Q
R
Q
L
S
K
L
W
K
E
E
L
Chimpanzee
Pan troglodytes
XP_525729
1333
146376
S475
K
T
T
Q
R
Q
L
S
K
L
W
Q
E
E
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_540143
1333
147201
E476
K
T
T
R
K
Q
V
E
N
L
W
N
E
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q00519
1335
146500
S477
K
T
T
P
K
Q
L
S
K
S
W
N
E
E
L
Rat
Rattus norvegicus
P22985
1331
146224
S474
K
T
T
P
K
Q
L
S
K
S
W
N
E
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509432
1297
142673
G475
E
T
P
R
K
Q
T
G
R
F
W
D
E
S
L
Chicken
Gallus gallus
P47990
1358
149595
G501
K
T
C
R
E
L
A
G
R
D
W
N
E
K
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_688983
1351
148155
N492
A
T
C
N
K
L
L
N
R
Q
W
N
E
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P10351
1335
146909
G477
R
T
S
Q
L
M
V
G
Q
E
W
S
H
Q
L
Honey Bee
Apis mellifera
XP_001119950
1356
152206
G508
K
T
C
N
I
M
I
G
R
K
W
D
K
D
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q7G192
1321
144562
E465
I
R
C
K
E
I
E
E
F
L
S
G
K
V
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
90.4
N.A.
89.1
90.3
N.A.
70.4
72.3
N.A.
67.8
N.A.
52.6
52.4
N.A.
N.A.
Protein Similarity:
100
99.6
N.A.
95.4
N.A.
95.1
95.8
N.A.
82.3
84
N.A.
81.4
N.A.
69.5
70.5
N.A.
N.A.
P-Site Identity:
100
93.3
N.A.
53.3
N.A.
73.3
73.3
N.A.
33.3
33.3
N.A.
33.3
N.A.
26.6
26.6
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
80
N.A.
80
80
N.A.
60
53.3
N.A.
60
N.A.
60
53.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
37
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
10
0
19
0
28
0
% D
% Glu:
10
0
0
0
19
0
10
19
0
10
0
0
73
37
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
37
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
10
0
0
0
10
10
10
0
0
0
0
0
0
0
10
% I
% Lys:
64
0
0
10
46
0
0
0
37
10
0
10
19
10
0
% K
% Leu:
0
0
0
0
10
19
46
0
0
37
0
0
0
0
91
% L
% Met:
0
0
0
0
0
19
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
19
0
0
0
10
10
0
0
46
0
0
0
% N
% Pro:
0
0
10
19
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
28
0
55
0
0
10
10
0
10
0
10
0
% Q
% Arg:
10
10
0
28
19
0
0
0
37
0
0
0
0
0
0
% R
% Ser:
0
0
10
0
0
0
0
37
0
19
10
10
0
10
0
% S
% Thr:
0
91
46
0
0
0
10
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
19
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
91
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _